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ENTONOX® nitrous oxide/oxygen mixture provides the pain relieving properties of nitrous oxide with the benefits of additional oxygen without producing unconsciousness. It is a widely used analgesic for acute, short-term pain relief in a diverse range of clinical situations, from painful procedures to childbirth.

The low solubility of nitrous oxide in biological tissue and fluid means, in clinical practice, that medical nitrous oxide/oxygen mixtures provide rapid pain relief and elimination of the gas from the lungs. A further safety feature is the composition of the premixed product consisting of a mixture of 50% nitrous oxide and 50% oxygen to prevent hypoxia during administration.

Medical nitrous oxide/oxygen mixtures can be administered by inhalation through face or nose masks or mouthpieces provided either as two separate gases delivered through a blender device or as fixed 50:50 mixtures. Gas flow can be controlled by a demand-valve activated by the patient’s inspired breath. The equipment is designed to be portable and easy to use both inside and outside the hospital.

Because medical nitrous oxide/oxygen mixtures are administered by inhalation and therefore are non-invasive, there is no need to insert a cannula or set up an intravenous line, this means that analgesia/sedation with the mixtures does not need to be administered by a specialist anaesthetist but can be administered by trained staff such as paramedics, nurses and those authorised to administer the product

Please refer to the product data sheet for full details on ENTONOX.